Protein Domain : tRNA N(3)-methylcytidine methyltransferase METTL2/6/8-like IPR026113

Type  Family
Description  This family includes tRNA N(3)-methylcytidine methyltransferases METTL2, 6 and 8, O-methyltransferase 3 and methyltransferase-like protein Metl from Drosophila. These proteins are S-adenosyl-L-methionine-dependent methyltransferases that mediate N3-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Thr) and tRNA(Ser) [ , , , , , , ].tRNA N(3)-methylcytidine methyltransferase METTL2, 6 and 8 are part of a group of proteins known as TIPs (from tension-induced/inhibited protein) required for the recruitment of histone acetyltransferase p300 to specific promoters. TIP-6 is involved in the adipogenic cascade [ ]. O-methyltransferase 3 is up-regulated by phagocytic stimuli [].
Short Name  METTL2/6/8-like

0 Child Features

2 Gene Families

195 Genes

0 Ontology Annotations

0 Parent Features

14 Publications

USDA
InterMine logo
The Legume Information System (LIS) is a research project of the USDA-ARS:Corn Insects and Crop Genetics Research in Ames, IA.
LegumeMine || ArachisMine | CicerMine | GlycineMine | LensMine | LupinusMine | PhaseolusMine | VignaMine | MedicagoMine
InterMine © 2002 - 2022 Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom