Protein Domain : PQ-loop repeat IPR006603

Type  Repeat
Description  Some membrane bound proteins possess a pair of repeats each spanning two transmembrane helices connected by a loop [ ]. The PQ motif found on loop 2 is critical for the localisation of cystinosin to lysosomes []. However, the PQ motif appears not to be a general lysosome-targeting motif. It is thought to possess a more general function; most probably this involves a glutamine residue [].
Short Name  PQ-loop_rpt

0 Child Features

2 Gene Families

656 Genes

0 Ontology Annotations

0 Parent Features

14 Publications

USDA
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