v5.1.0.3
Glycine data from LIS
Type | Repeat |
Description | Some membrane bound proteins possess a pair of repeats each spanning two transmembrane helices connected by a loop [ ]. The PQ motif found on loop 2 is critical for the localisation of cystinosin to lysosomes []. However, the PQ motif appears not to be a general lysosome-targeting motif. It is thought to possess a more general function; most probably this involves a glutamine residue []. |
Short Name | PQ-loop_rpt |