v5.1.0.3
Glycine data from LIS
Type | Domain |
Description | This domain is found both alone (in the costars family of proteins) and at the C terminus of actin-binding Rho-activating protein (ABRA). It binds to actin, and in muscle regulates the actin cytoskeleton and cell motility [ , ]. It has a winged helix-like fold consisting of three α-helices and four antiparallel beta strands. Unlike typical winged helix proteins it does not bind to DNA, but contains a hydrophobic groove which may be responsible for interaction with other proteins []. |
Short Name | Costars_dom |