Protein Domain : Magnesium-dependent phosphatase-1, eukaryotic/archaeal-type IPR010036

Type  Family
Description  This entry represents two closely related clades of sequences from eukaryotes and archaea, however, some uncharacterised bacterial sequences are also included in this family. The mouse enzyme has been characterised as a phosphatase and has been positively identified as a member of the haloacid dehalogenase (HAD) superfamily by site-directed mutagenesis of the active site residues [ , ]. Its structure is similar to other HAD members but MDP-1 appears to be equally able to dephosphorylate phosphotyrosine and closed-ring phosphosugars [].
Short Name  MDP_1_eu_arc

1 Child Features

1 Gene Families

161 Genes

1 Ontology Annotations

0 Parent Features

14 Publications

USDA
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