Protein Domain : Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase domain IPR004399

Type  Domain
Description  This entry represents a bifunctional enzyme, phosphomethylpyrimidine (HMP-P) kinase ( )/Hydroxymethylpyrimidine (HMP) kinase ( ), the ThiD/J protein of thiamine biosynthesis. It catalyses two consecutive phosphorylation reactions in the thiamine phosphate biosynthesis pathway, first phosphorylating HMP to HMP-P, and then HMP-P to HMP-PP [ ]. The protein is commonly observed within operons containing other thiamine biosynthesis genes. Numerous examples are fusion proteins with other thiamine-biosynthetic domains.
Short Name  HMP/HMP-P_kinase_dom

0 Child Features

0 Gene Families

94 Genes

2 Ontology Annotations

1 Parent Features

13 Publications

USDA
InterMine logo
The Legume Information System (LIS) is a research project of the USDA-ARS:Corn Insects and Crop Genetics Research in Ames, IA.
LegumeMine || ArachisMine | CicerMine | GlycineMine | LensMine | LupinusMine | PhaseolusMine | VignaMine | MedicagoMine
InterMine © 2002 - 2022 Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom