Protein Domain : Thiamine phosphate synthase/TenI IPR022998

Type	Domain
Description	Thiamine phosphate synthase (TPS) catalyses the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5- (beta-hydroxyethyl)thiazole phosphate to yield thiamine phosphate in the thiamine biosynthesis pathway [ ].TenI, a protein from Bacillus subtilis that regulates the production of several extracellular enzymes by reducing alkaline protease production belongs to this group [ ]. While TenI shows high sequence similarity with thiamin phosphate synthase [], the purified protein has no thiamin phosphate synthase activity. Instead, it is a thiazole tautomerase [].This entry refers to a domain found in thiamine phosphate synthase, thiazole tautomerase and similar proteins.
Short Name	ThiamineP_synth_TenI