Protein Domain : Phosphoacetylglucosamine mutase IPR016657

Type	Family
Description	This group represents a phosphoacetylglucosamine mutase (PAGM; also known as phosphoglucomutase 3 or N-acetylglucosamine-phosphate mutase [ ]). It is an essential enzyme found in eukaryotes that reversibly catalyzes the conversion of GlcNAc-6-phosphate into GlcNAc-1-phosphate as part of the UDP-N-acetylglucosamine (UDP-GlcNAc) biosynthetic pathway. UDP-GlcNAc is an essential metabolite that serves as the biosynthetic precursor of many glycoproteins and mucopolysaccharides. PAGM is a member of the alpha-D-phosphohexomutase superfamily [], which catalyzes the intramolecular phosphoryl transfer of sugar substrates []. The alpha-D-phosphohexomutases have four domains with a centrally located active site formed by four loops, one from each domain []. All four domains are included in this alignment model.
Short Name	PAGM