Protein Domain : Asp/Glu racemase, active site 1 IPR018187

Type	Active_site
Description	Aspartate racemase ( ) and glutamate racemase ( ) are two evolutionary related bacterial enzymes that do not seem to require a cofactor for their activity [ ]. Glutamate racemase, which interconverts L-glutamate into D-glutamate, is required for the biosynthesis of peptidoglycan and some peptide-based antibiotics such as gramicidin S.In addition to characterised aspartate and glutamate racemases, this family also includes a hypothetical protein from Erwinia carotovora and one from Escherichia coli (ygeA). Two conserved cysteines are present in the sequence of these enzymes. They are expected to play a role in catalytic activity by acting as bases in proton abstraction from the substrate. This entry represents a conserved region containing the first cysteine.
Short Name	Asp/Glu_racemase_AS_1