Protein Domain : Bet3 family IPR016721

Type	Family
Description	This entry includes Bet3 (also known as TRAPPC3) and Bet3-like (TRAPPC3L) proteins from eukaryotes. They seem to be involved in vesicle-mediated transport. Yeast Bet3 is a core component of transport protein particle (TRAPP) complexes I-III. The TRAPPI complex recognises the coat (COPII) on ER-derived vesicles, whereas the TRAPPII complex recognises the coat (COPI) on Golgi-derived vesicles [ ]. TRAPPIII is responsible for vesicular transport from early endosomes to Golgi, facilitating Atg9 cycling in autophagy [].Mammalian TRAPPs complexity is increased by the presence of multiple TRAPP homologues and novel subunits or binding proteins that are not part of the yeast TRAPP complexes []. Bet3 and its homologue Bet3-like are both components of the mammalian TRAPP complex [].
Short Name	Bet3