Protein Domain : Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal IPR015211

Type  Domain
Description  This C-terminal domain is found in peptidases belonging to MEROPS peptidase family M1, particularly: aminopeptidase-1 of Caenorhabditis elegans, aminopeptidase O, aminopeptidase B and the bifunctional leukotriene A4 (LTA-4) hydrolase/aminopeptidase. The domain adopts a structure consisting of two layers of parallel α-helices, five in the inner layer and four in the outer, arranged in an antiparallel manner, with perpendicular loops containing short helical segments on top. It is required for the formation of a deep cleft harbouring the catalytic Zn2+ site in leukotriene A4 hydrolase [ ].
Short Name  Peptidase_M1_C

0 Child Features

0 Gene Families

51 Genes

2 Ontology Annotations

0 Parent Features

12 Publications

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