Ontology Term : Pfam:PF14705 Costars EMBL-EBI

Description  This domain is found both alone and at the C-terminus of actin-binding Rho-activating protein (ABRA). It binds to actin, and in muscle regulates the actin cytoskeleton and cell motility [1-2]. It has a winged helix-like fold consisting of three alpha-helices and four antiparallel beta strands. Unlike typical winged helix proteins it does not bind to DNA, but contains a hydrophobic groove which may be responsible for interaction with other proteins [3].
Namespace  Domain

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56 Data Sets

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1 Ontology

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222 Ontology Annotations

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