Ontology Term : Pfam:PF02792 Mago nashi protein EMBL-EBI

Description  This family was originally identified in Drosophila and called mago nashi, it is a strict maternal effect, grandchildless-like, gene [3]. The human homologue has been shown to interact with an RNA binding protein Swiss:Q9Y5S9 [1]. An RNAi knockout of the C. elegans homologue causes masculinization of the germ line (Mog phenotype) hermaphrodites, suggesting it is involved in hermaphrodite germ-line sex determination [2]. Mago nashi has been found to be part of the exon-exon junction complex that binds 20 nucleotides upstream of exon-exon junctions [4].
Namespace  Family

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56 Data Sets

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1 Ontology

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347 Ontology Annotations

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