GO Term : GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity Gene Ontology

Description	Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
Namespace	molecular_function
Obsolete	false