Ontology Term : Pfam:PF03455 dDENN domain EMBL-EBI

Description  This region is always found associated with Pfam:PF02141. It is predicted to form a globular domain [1]. Although not statistically supported it has been suggested that this domain may be similar to members of the Rho/Rac/Cdc42 GEF family [1]. This N-terminal region of DENN folds into a longin module, consisting of a central antiparallel beta-sheet layered between helix H1 and helices H2 and H3 (strands S1-S5). Rab35 interacts with dDENN via residues in helix 1 and in the loop S3-S4 [2].
Namespace  Domain

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51 Data Sets

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1 Ontology

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106 Ontology Annotations

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