Ontology Term : Pfam:PF01812 5-formyltetrahydrofolate cyclo-ligase family EMBL-EBI
Description  5-formyltetrahydrofolate cyclo-ligase or methenyl-THF synthetase EC:6.3.3.2 catalyses the interchange of 5-formyltetrahydrofolate (5-FTHF) to 5-10-methenyltetrahydrofolate, this requires ATP and Mg2+ [1]. 5-FTHF is used in chemotherapy where it is clinically known as Leucovorin [2].
Namespace  Family
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