v5.1.0.3
Glycine data from LIS
Type | Family |
Description | Mucin-20 (MUC20) was identifiied as a gene that is up-regulated in the renal tissues of patients with immunoglobulin A nephropathy [ ]. It is a regulator of the Met signaling cascade. MUC20 associates with Met which is the hepatocyte growth factor (HGF) receptor, and has a role in suppressing the Grb2-Ras pathway. Production of MUC20 reduced HGF-induced matrix metalloproteinase expression and proliferation, which require the Grb2-Ras pathway []. |
Short Name | MUC20 |